GWAS-related eQTLs across different cancer types
We identified 337,131 eQTLs that overlap with GWAS linkage disequilibrium (LD) regions (r² ≥ 0.5).
|
Cancer type
|
eQTL type
|
tagSNP
|
Gene position (hg19)
|
p-value
|
|||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| THYM | cis | rs2275426 | 1 | rs7524495 | chr1:46266932 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |
| THYM | cis | rs7589728 | 1 | rs75309929 | chr2:88524377 | THNSL2 | chr2:88469835-88486145:+ | -0.5 | -4.23 | 5.34E-5 | Plasma clusterin levels |
| THYM | cis | rs7552404 | 1 | rs7533888 | chr1:76160449 | ACADM | chr1:76190043-76229353:+ | 0.3 | 4.24 | 5.21E-5 | Blood metabolite levels;Acylcarnitine levels |
| THYM | cis | rs4660306 | 1 | rs7534467 | chr1:45988691 | CCDC163P | chr1:45960581-45965646:- | -0.86 | -14.78 | 2.3E-26 | Homocysteine levels |
| THYM | cis | rs7552404 | 1 | rs7534754 | chr1:76185308 | ACADM | chr1:76190043-76229353:+ | 0.3 | 4.24 | 5.21E-5 | Blood metabolite levels;Acylcarnitine levels |
| THYM | cis | rs4660306 | 1 | rs7536557 | chr1:45992114 | CCDC163P | chr1:45960581-45965646:- | -0.76 | -12.27 | 2.68E-21 | Homocysteine levels |
| THYM | cis | rs73726531 | 1 | rs75379431 | chr6:18128481 | NHLRC1 | chr6:18120718-18122851:- | -1.1 | -4.37 | 3.12E-5 | Thiopurine S-methyltransferase activity |
| THYM | cis | rs2275426 | 1 | rs7539932 | chr1:46292354 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs7540325 | chr1:46338217 | CCDC163P | chr1:45960581-45965646:- | -0.49 | -5.85 | 6.8E-8 | Body mass index |
| THYM | cis | rs73726531 | 1 | rs75407001 | chr6:18120293 | NHLRC1 | chr6:18120718-18122851:- | -1.06 | -4.39 | 2.95E-5 | Thiopurine S-methyltransferase activity |
| THYM | cis | rs7552404 | 1 | rs7548962 | chr1:76139266 | ACADM | chr1:76190043-76229353:+ | 0.3 | 4.24 | 5.22E-5 | Blood metabolite levels;Acylcarnitine levels |
| THYM | cis | rs2275426 | 1 | rs7550746 | chr1:46351719 | CCDC163P | chr1:45960581-45965646:- | -0.5 | -5.94 | 4.7E-8 | Body mass index |
| THYM | cis | rs7552404 | 1 | rs7552404 | chr1:76135946 | ACADM | chr1:76190043-76229353:+ | 0.3 | 4.24 | 5.21E-5 | Blood metabolite levels;Acylcarnitine levels |
| THYM | cis | rs2275426 | 1 | rs7556436 | chr1:46363880 | CCDC163P | chr1:45960581-45965646:- | 0.49 | 6 | 3.55E-8 | Body mass index |
| THYM | cis | rs2275426 | 1 | rs7556615 | chr1:46461369 | CCDC163P | chr1:45960581-45965646:- | -0.47 | -5.73 | 1.15E-7 | Body mass index |